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Each capsule contains.29 mg tizanidine side hydrochloride, equivalent to side 2 mg tizanidine base. Keep these considerations in side mind if your zanaflex doctor prescribes tizanidine oral tablet for you. Side Effects side effects The following adverse reactions are described elsewhere in other sections of zanaflex the zanaflex prescribing information: Clinical Trials Experience Because clinical studies side are conducted under widely varying conditions, adverse reaction rates observed in the clinical studies. What happens if I overdose? Tizanidine oral tablet is available as both a generic and side brand-name drug. See Contraindications ( 4 ) and Clinical Pharmacology (.3 ) Ciprofloxacin Concomitant use of ciprofloxacin and Zanaflex is contraindicated. Anxiety back pain constipation depression diarrhea dizziness or lightheadedness, especially when getting up from lying or sitting position drowsiness dry zanaflex mouth fatigue heartburn increased muscle spasms or tone increased sweating muscle weakness nausea runny nose skin rash sleepiness stomach. The median dose during the plateau phase ranged from 2028 mg/day. Warnings and Precautions, hypotension, tizanidine is an zanaflex 2-adrenergic agonist that can zanaflex produce hypotension. The absolute oral bioavailability of tizanidine is approximately 40 (CV 24 due to extensive first-pass hepatic metabolism. Zanaflex Capsules and Zanaflex tablets are bioequivalent to each other under fasting conditions effects (more than 3 hours after a meal but not zanaflex under fed conditions (within 30 minutes of a meal). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription and herbal medications you are taking. After making effects any changes in how you take Zanaflex, contact your doctor if you notice any change in how well the medicine works or if it causes increased side effects. Clinical Studies Tizanidines capacity to reduce increased muscle tone associated with spasticity was demonstrated in two adequate and well controlled studies in patients with multiple sclerosis or spinal cord injury (Studies 1 and 2). Figure 3: side Seven Week StudyMean Change in Muscle Tone.52.5 Hours effects After Dosing zanaflex as Measured by the Ashworth Scale 95 Confidence Interval (A Negative Ashworth Score Signifies an Improvement in Muscle Tone from Baseline) Medication Guide patient information Serious Drug. Always effects take tinazidine exactly as prescribed by your doctor. The side effects listed below are not experienced by everyone who takes this medication. It is not known whether Zanaflex will harm an unborn baby. Syncope has been reported in the post marketing setting. If you dont take this drug at all, your muscle spasms may not improve. Symptoms can include: trouble breathing itching swelling of your throat or tongue If you have an allergic reaction, call your doctor or local poison control center right away. If you miss a dose of this medicine take it as soon as possible, if you remember within an hour or so of the missed dose. What happens if I miss a dose? See Drug Interactions (.5,.6 ) Hallucinosis/Psychotic-Like Symptoms Zanaflex use has been associated with hallucinations. Dont put this medication in your cars glove compartment or leave it in the car.

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